GeneMark: Relevant References

News | Books | Gene Finding Journal Publications | Issues in Gene Finding | DNA, proteins and cell systems modeling and analysis

 

News

Lomsadze A., Burns P.D. and Borodovsky M.
"Integration of mapped RNA-Seq reads into automatic training of eukaryotic gene finding algorithm."
Nucleic Acids Research, 2014, July 2, doi: 10.1093/nar/gku557
PubMed | Article

Wu A., Jenkins J., Salse J., Hellsten U., Murat F., et al
"Sequencing of diverse mandarin, pummelo and orange genomes reveals complex history of admixture during citrus domestication"
Nature Biotechnology, 2014, doi:10.1038/nbt.2906.
PubMed | Article

Wang W., Haberer G., Gundlach H., Gläßer C., Nussbaumer T., et al
"The Spirodela polyrhiza genome reveals insights into its neotenous reduction fast growth and aquatic lifestyle"
" Nature Communications, 2014, 5:3311. doi: 10.1038/ncomms4311.
PubMed | Article

Read BA, Kegel J, Klute MJ, Kuo A, Lefebvre SC, et al.
"Pan genome of the phytoplankton Emiliania underpins its global distribution."
Nature. 2013, 499(7457):209-13
PubMed | Article


Books

Borodovsky M. and Ekisheva S.
Problems and Solutions in Biological Sequence Analysis
Cambridge University Press, 2006
Publisher | DOI | Amazon| Review | Review 2 | Russian Translation


Gene Finding

Tang S., Lomsadze G., and M. Borodovsky
"Identification of Protein Coding Regions in RNA Transcript"
(Revised version submitted)
GeneMarkS-T software (beta version) can be downloaded here.

GeneMark-ET
Lomsadze A., Burns P.D. and Borodovsky M.
"Integration of mapped RNA-Seq reads into automatic training of eukaryotic gene finding algorithm."
Nucleic Acids Research, 2014, July 2, doi: 10.1093/nar/gku557
PubMed | Article

MetaGeneMark
Zhu W., Lomsadze A. and Borodovsky M.
"Ab initio gene identification in metagenomic sequences."
Nucleic Acids Research, 2010, Vol.38, No.12, e132, doi: 10.1093/nar/gkq275
PubMed | Article | Supplemental Materials

GeneMark-ES, version 2
Ter-Hovhannisyan V., Lomsadze A., Chernoff Y. and Borodovsky M.
"Gene prediction in novel fungal genomes using an ab initio algorithm with unsupervised training."
Genome Research, 2008, Dec 18(12):1979-90
PubMed | Article | Supplemental Materials

GeneMark-ES, version 1
Lomsadze A., Ter-Hovhannisyan V., Chernoff Y. and Borodovsky M.
"Gene identification in novel eukaryotic genomes by self-training algorithm."
Nucleic Acids Research, 2005, Vol. 33, No. 20, 6494-6506
PubMed | Article

GeneMark Web Server
Besemer J. and Borodovsky M.
"GeneMark: web software for gene finding in prokaryotes, eukaryotes and viruses."
Nucleic Acids Research, 2005, Vol. 33, Web Server Issue, pp. W451-454
PubMed | Article

VIOLIN
Mills R., Rozanov M., Lomsadze A., Tatusova T. and Borodovsky M.
"Improving gene annotation in complete viral genomes."
Nucleic Acids Research, 2003, Vol. 31, No. 23, 7041-7055
PubMed | Article

GeneMarkS
Besemer J., Lomsadze A. and Borodovsky M.
"GeneMarkS: a self-training method for prediction of gene starts in microbial genomes. Implications for finding sequence motifs in regulatory regions."
Nucleic Acids Research, 2001, Vol. 29, No. 12, 2607-2618
PubMed | Article

Heuristic Models
Besemer J. and Borodovsky M.
"Heuristic approach to deriving models for gene finding."
Nucleic Acids Research, 1999, Vol. 27, No. 19, pp. 3911-3920
PubMed | Article

Frame-by-Frame
Shmatkov A.M., Melikyan A.A., Chernousko F.L. and Borodovsky M.
"Finding prokaryotic genes by the 'frame-by-frame' algorithm: targeting gene starts and overlapping genes."
Bioinformatics, 1999, Vol. 15, No. 11, pp. 874-886
PubMed | Article

GeneMark-Genesis
Hayes W. and Borodovsky M.
"How to interpret an anonymous bacterial genome: machine learning approach to gene identification."
Genome Research, 1998, Vol. 8, No. 11, pp. 1154-1171
PubMed | Article

GeneMark.hmm
Lukashin A. and Borodovsky M.
"GeneMark.hmm: new solutions for gene finding."
Nucleic Acids Research, 1998, Vol. 26, No. 4, pp. 1107-1115
PubMed | Article

GeneMark
Borodovsky M. and McIninch J.
"GeneMark: parallel gene recognition for both DNA strands."
Computers & Chemistry, 1993, Vol. 17, No. 19, pp. 123-133
Abstract | Article

Borodovsky M.Yu., McIninch J.
"Recognition of genes in DNA sequence with ambiguities"
Biosystems. , 1993;Vol 30(1-3), pp.161-71
PubMed | Article

Borodovsky M.Yu., Sprizhitskii Y.A., Golovanov E.I., and Aleksandrov A.A.
"Statistical Patterns in Primary Structures of the Functional Regions of the Genome in Escherichia Coli."
Molekular Biology, 1986, Vol. 20, pp. 826-833, 833-840, 1144-1150
Article


Issues in Gene Finding back to top

Antonov I, Coakley A, Atkins JF, Baranov PV, Borodovsky M.
"Identification of the nature of reading frame transitions observed in prokaryotic genomes."
Nucleic Acids Research, 2013, 41(13):6514-30
PubMed | Article

Burns PD, Li Y, Ma J, Borodovsky M.
"UnSplicer: mapping spliced RNA-seq reads in compact genomes and filtering noisy splicing."
Nucleic Acids Research, 2013 Nov 19
PubMed | Article | Supplemental Materials

Antonov I., Baranov P. and Borodovsky M.
"GeneTack database: genes with frameshifts in prokaryotic genomes and eukaryotic mRNA sequences"
Nucleic Acids Research, Vol. 41, No. D1 (2013):D152-D156.
PubMed | Article

Tang S., Antonov I. and Borodovsky M.
"MetaGeneTack: ab initio detection of frameshifts in metagenomic sequences."
Bioinformatics, Vol. 29, No. 1 (2013):114-116.
PubMed | Article

Martin J., Zhu W., Passalacqua K., Bergman N. and Borodovsky M.
"Bacillus anthracis genome organization in light of whole transcriptome sequencing."
BMC Bioinformatics, 2010, 11(Suppl 3):S10 doi:10.1186/1471-2105-11-S3-S10
PubMed | Article | Supplemental Materials

Antonov I. and Borodovsky M.
"GeneTack: Frameshift Identification in Protein Coding Sequences by the Viterbi Algorithm."
J Bioinformatics and Computational Biology, Vol. 8, No. 3 (2010):1-17.
Medline | Article

Azad R.K. and Borodovsky M.Y.
"Probabilistic methods of identifying genes in prokaryotic genomes: connections to the HMM theory."
Briefings in Bioinformatics, 2004, Vol. 5, No. 2, pp. 118-130
PubMedArticle

Azad R.K. and Borodovsky M.
"Effects of choice of DNA sequence model structure on gene identification accuracy."
Bioinformatics, 2004, Vol. 20, No. 7, pp. 993-1005
PubMedArticle


DNA, proteins and cell systems modeling and analysis back to top

Read BA, Kegel J, Klute MJ, Kuo A, Lefebvre SC, et al.
"Pan genome of the phytoplankton Emiliania underpins its global distribution."
Nature. 2013, 499(7457):209-13
PubMed| Article

Junhuan Xu et al.
Gene discovery in EST sequences from the wheat leaf rust fungus Puccinia triticina sexual spores, asexual spores and haustoria, compared to other rust and corn smut fungi.
BMC Genomics, 2011 Mar 24; 10.1186/1471-2164-12-161
Article

Blanc G, Duncan G, Agarkova I, Borodovsky M, Gurnon J, Kuo A, et al.
"The Chlorella variabilis NC64A genome reveals adaptation to photosymbiosis, coevolution with viruses, and cryptic sex"
Plant Cell. 2010, 22(9):2943-55.
PubMed| Article

Guillaume Blanc et al.
The Chlorella variabilis NC64A Genome Reveals Adaptation to Photosymbiosis, Coevolution with Viruses, and Cryptic Sex
The Plant Cell, 2010 Sep 17; 10.1105/tpc.110.076406.
Article

Jason Stajich et al.
Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus)
Proc Natl Acad Sci USA, 2010 Jun 29; 107(26):11889-94.
Article

Svetlana Ekisheva and Mark Borodovsky
"Uniform Accuracy of the Maximum Likelihood Estimates for Probabilistic Models of Biological Sequences."
Methodology and Computing in Applied Probability, 2009 Feb; 10.1007/s11009-009-9125-7
Article

Mitrophanov A.Yu. and Borodovsky M.
"Convergence rate estimation for the TKF91 model of biological sequence length evolution"
Math Biosci., 2007 Oct;209(2):470-85. Epub 2007 Mar 13.
PubMed | Article

Piriyapongsa J., Polavarapu N., Borodovsky M. and McDonald J.
"Exonization of the LTR transposable elements in human genome"
BMC Genomics, 2007 Aug 28;8:291.
PubMedArticle

Mitrophanov A.Yu., Churchward G. and Borodovsky M.
"Control of Streptococcus pyogenes virulence: Modeling of the CovR/S signal transduction system"
J Theor Biol., 2007 May 7;246(1):113-28. Epub 2006 Nov 21.
PubMedArticle

Aydin Z., Altunbasak Y. and Borodovsky M.
"Protein secondary structure prediction for a single-sequence using hidden semi-Markov models."
BMC Bioinformatics, 2006 Mar 30;7:178
PubMedArticle

Kim S.B., Tsui K. and Borodovsky M.
"Multiple testing in large-scale contingency tables: inferring patterns of pair-wise amino acid association in beta-sheets"
Int. J. Bioinformatics Research and Applications, 2006, Vol. 2, No. 2, pp 193-217
Article

Ekisheva S. and Borodovsky M.
"Probabilistic models for biological sequences: selection and Maximum Likelihood estimation"
Int. J. Bioinformatics Research and Applications, 2006, Vol. 2, No. 3, pp 305-324
Article

Mitrophanov A.Yu. and Borodovsky M.
"Statistical significance in biological sequence analysis."
Briefings in Bioinformatics, 2006, Vol. 7, No.1, pp. 2-24
PubMedArticle

Mitrophanov A.Yu., Lomsadze A. and Borodovsky M.
"Sensitivity of hidden Markov models."
Journal of Applied Probability, 2005, Vol. 42, pp. 632-642
Article

Kattenhorn L.M., Mills R., Wagner M., Lomsadze A., Makeev V., Borodovsky M., Ploegh H.L. and Kessler B.M
"Identification of Proteins Associated with Murine Cytomegalovirus Virions."
Journal of Virology, 2004, Vol. 78, No. 20, pp. 11187-11197
PubMedArticle

Jean-F. Tomb et al.
The complete genome sequence of the gastric pathogen Helicobacter pylori
Nature, 1997 August 7, 388(6642):539-47.
Article

Carol Bult et al.
Complete Genome Sequence of the Methanogenic Archaeon, Methanococcus jannaschii
Science, 1996 Aug; Vol. 273. no. 5278, pp. 1058 - 1073
Article

Kleffe J. and Borodovsky M.
"First and second moment of counts of words in random texts generated by Markov chains"
Comput. Appl. Biosci., 1992, Vol. 8, No. 5, pp. 433-441
PubMedArticle

 
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